Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.
Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.
You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.
oody pharmaceuticalsTadalafil 5mg is used to treat erectile dysfunction, the inability to have and maintain an erection, and benign prostatic hyperplasia. Dose and duration of treatment may vary based on your erectile dysfunction, BPH symptoms and your medical condition. In some cases, you may experience side effects such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing.
Take special attention to these side effects which may be mild or serious. If you experience serious side effects such as dizziness, fainting and rapid heartbeat, stop taking Tadalafil and get medical attention immediately. These side effects may require medical treatment and/or a new prescription is needed to treat. You are advised to seek advice before taking Tadalafil.
Bone densityDose and duration of treatment may vary based on erectile dysfunction, BPH symptoms and your medical condition. In some cases, you may experience side effects such as dizziness, fainting and rapid heartbeat, stop taking Tadalafil and get medical attention immediately.
Dosage and use restrictions apply. Please consult your doctor before taking any medicine.
Medicines have been supplied for your use only. This is not a complete list of medications available for purchase in the USA from our company.
Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As a PDE5 inhibitor, Tadalafil helps relax the walls of the blood vessels, which increases blood flow. That’s important because enough blood can flow through a heart to keep up an erection. When that happens, the heart’s blood vessels can’t open properly, which leads to a prolonged erection (priapism).
If you have other health conditions, such as heart failure or high blood pressure, which are how your body naturally produces Tadalafil, you may be at higher risk for getting ED.
ED is caused by a combination of both things—the physical process of getting an erection and the psychological process of deciding that you’re ready to have sex. When you’re diagnosed with ED, you should know which conditions can make it more likely that you’ll get an erection, especially if you have heart disease, high blood pressure, high cholesterol, or other health issues. That’s because ED can be caused by both things, and that makes it more difficult to get an erection if you have heart disease, high blood pressure, high cholesterol, or other health issues.
If you have heart disease or high blood pressure, discuss with your doctor how Tadalafil can help. In addition, you should also be aware that Tadalafil can interact with other medications you’re taking, including some that you should only take with your doctor’s approval.
If you have a history of cardiovascular problems, such as heart attack or stroke, start taking Tadalafil before deciding to have sex. That’s because having an erection can increase the risk of heart disease, high blood pressure, or other cardiovascular problems. If you have a history of cardiovascular problems, such as heart disease or high blood pressure, tell your doctor before taking Tadalafil.
Also, let your doctor know if you are taking any other medications, including other PDE5 inhibitors you might be taking. This will help reduce the likelihood of getting ED.
ED can also be caused by a combination of both things. If you have ED, you often find yourself getting an erection any time you’re sexually excited or have sex. However, that’s not the same thing as having an.
If you have another condition that’s causing ED, such as depression, ask your doctor how it’s done. That’s because having an ED can sometimes make it more difficult to get an erection. That’s because a stronger, longer-lasting erection can damage your mental state.
If you’re in the last half of pregnancy, it’s very important that you know what's inside your Viagra pills. That way, your doctor can make sure that it's safe for you during your delivery period. And if you're planning on having sex in between, having an erection during the delivery can also be a concern.
If you have another condition that’s causing ED, such as liver or kidney disease, tell your doctor before taking Tadalafil. That’s because taking Tadalafil can sometimes make it more difficult to get an erection.
ED can also sometimes be caused by a combination of both things.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
Citedriers [X] and [Y]. online consultation. [Revised in November 2009] [Accessed on November 08th, 2023]https://www.medicines.org.in/CDSCO/drugsCautions: (a) Use in pregnant or lactating individuals. Consult a doctor if you have any underlying medical conditions, and if so posted to the pharmacy or hospital. Cautions: (b) In patients with low blood pressure, when used for an extended period, it may result in an increased risk of side effects. (c) In elderly patients, consult your doctor. (d) Before starting treatment, tell your doctor about all your previous medical conditions, especially those involving the absorption of drugs. (e) Do not take Tadalafil if you are taking nitrates (eg, isosorbide, isosorbide mononitrate) or riociguat (eg, cGMP-Out). (f) Before using Tadalafil, inform your doctor about all the medications you are taking, especially: (a) non-steroidal anti-inflammatory drugs (NSAIDs), including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, or others (eg, indometacin); and (b) SaleVERHOT/TRAZA. (c) If you are using any of the medications for the first time, it is recommended that you inform your doctor before taking Tadalafil. It is not recommended to split, crush, or chew Tadalafil. [XI] and [YI] and international patient quality-of-life scales were used to assess the effectiveness and safety of Tadalafil in combination with Tamsulosin. [XIIII] and [YI] and positive family history were used to identify patients with positive Tadalafil or negative Tadalafil family history. [XI] was also used to determine the safety of Tadalafil in combination with Tamsulosin. [I] and [II] and quality-of-life questionnaire were used to assess the quality of life in patients with left ventricular hypertrophy. [XI] was also used to assess the efficacy of Tadalafil in patients with benign prostatic hyperplasia. [I] and [II] and positive family history were used to identify patients with positive Tadalafil or negative Tadalafil family history. [XI] was also used to determine the safety of Tadalafil in patients with pulmonary arterial hypertension. [I] was also used to assess the efficacy of Tadalafil in patients with postmarketing experience with Tadalafil. [I] and international patient quality-of-life questionnaire was used to assess the quality of life in patients with benign prostatic hyperplasia. [I] was also used to assess the efficacy of Tadalafil in patients with pulmonary arterial hypertension. (a) [XI] in combination with Tamsulosin.
Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.
You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.
There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-
• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).
• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets
for chest pain or use Rectogesic ointment?
• Nicorandil (Ikorel), used to treat angina
• Cimetidine, used to treat stomach or duodenal (peptic) ulcers
• Theophylline, used to treat asthma
• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin
• Anti-fungals such as itraconazole and ketoconazole
• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone
• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide
• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat
• Recreational drugs:- amyl nitrate (poppers)
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.
How to split a medical questionnaireIf you complete a short medical questionnaire and are prescribed Tadalafil as part of a stronger medical history, you may be asked to take one of the following:
You should complete the medical history you provide with your medication, including any of the following:
• You are being treated for a heart or blood pressure condition. Tadalafil allows for a correct diagnosis.
• You are taking a medicine to treat high blood pressure.
• You are having kidney or liver problems.
• You are having other medical conditions
• You are taking to make you Tadalafil
• You are being treated for yourpec
• Tadalafil is not suitable for you
You should complete the full medical questionnaire, even if your doctor has asked you to do so as some can refer to the total questionnaire as a group. You may also be asked to answer a few questions about your health. If you are not sure, than on “ still how would you describe your best efforts?”
You should discuss your medical questionnaire with your GP as part of the full medical consultation.”
You should be asked to3 list any health conditions you have with Tadalafil.
Stade de France Pharmacy